WHO Zika Virus, Microcephaly and Guillain-Barré Syndrome Situation Report, 15 December 2016

Report
from World Health Organization
Published on 15 Dec 2016 View Original

Key updates

  • Countries and territories reporting mosquito-borne Zika virus infections for the first time in the past week:

  • None

  • Countries and territories reporting microcephaly and other central nervous system (CNS) malformations potentially associated with Zika virus infection for the first time in the past week:

  • None

  • Countries and territories reporting Guillain-Barré syndrome (GBS) cases associated with Zika virus infection for the first time in the past week:

  • None

  • A traveler returned from Angola to France and presented with clinical signs and symptoms and serologic signs compatible with Zika virus infection. However, previous yellow fever vaccination and sero-positivity for other flaviviruses preclude the conclusive diagnosis of Zika virus infection because of the possibility of cross-reaction. Further investigations to determine if there is ongoing Zika virus transmission in Angola are ongoing.

Analysis

  • Overall, the global risk assessment has not changed. Zika virus continues to spread geographically to areas where competent vectors are present. Although a decline in cases of Zika infection has been reported in some countries, or in some parts of countries, vigilance needs to remain high.

Situation

  • Seventy-five countries and territories (Fig. 1, Table 1) have reported evidence of mosquitoborne Zika virus transmission since 2007 (69 with reports from 2015 onwards), of which:

o Fifty-eight with a reported outbreak from 2015 onwards (Fig. 2, Table 1).

o Seven with having possible endemic transmission or evidence of local mosquitoborne Zika infections in 2016.

o Ten with evidence of local mosquito-borne Zika infections in or before 2015, but without documentation of cases in 2016, or with the outbreak terminated.

  • Thirteen countries have reported evidence of person-to-person transmission of Zika virus (Table 2).

  • Twenty-nine countries or territories have reported microcephaly and other CNS malformations potentially associated with Zika virus infection, or suggestive of congenital infection (Table 3).

  • Twenty countries or territories have reported an increased incidence of GBS and/or laboratory confirmation of a Zika virus infection among GBS cases (Table 4).