WHO Zika Virus, Microcephaly and Guillain-Barré Syndrome Situation Report, 15 December 2016
Countries and territories reporting mosquito-borne Zika virus infections for the first time in the past week:
Countries and territories reporting microcephaly and other central nervous system (CNS) malformations potentially associated with Zika virus infection for the first time in the past week:
Countries and territories reporting Guillain-Barré syndrome (GBS) cases associated with Zika virus infection for the first time in the past week:
A traveler returned from Angola to France and presented with clinical signs and symptoms and serologic signs compatible with Zika virus infection. However, previous yellow fever vaccination and sero-positivity for other flaviviruses preclude the conclusive diagnosis of Zika virus infection because of the possibility of cross-reaction. Further investigations to determine if there is ongoing Zika virus transmission in Angola are ongoing.
- Overall, the global risk assessment has not changed. Zika virus continues to spread geographically to areas where competent vectors are present. Although a decline in cases of Zika infection has been reported in some countries, or in some parts of countries, vigilance needs to remain high.
- Seventy-five countries and territories (Fig. 1, Table 1) have reported evidence of mosquitoborne Zika virus transmission since 2007 (69 with reports from 2015 onwards), of which:
o Fifty-eight with a reported outbreak from 2015 onwards (Fig. 2, Table 1).
o Seven with having possible endemic transmission or evidence of local mosquitoborne Zika infections in 2016.
o Ten with evidence of local mosquito-borne Zika infections in or before 2015, but without documentation of cases in 2016, or with the outbreak terminated.
Thirteen countries have reported evidence of person-to-person transmission of Zika virus (Table 2).
Twenty-nine countries or territories have reported microcephaly and other CNS malformations potentially associated with Zika virus infection, or suggestive of congenital infection (Table 3).
Twenty countries or territories have reported an increased incidence of GBS and/or laboratory confirmation of a Zika virus infection among GBS cases (Table 4).