Attachments
Key Points:
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Epidemic remains active. The epidemic remains active and evolving, with varying transmission dynamics across the country. While there is a notable decline in weekly incident cases, sustained transmission is ongoing in identified hotspots. Todate 79% (115/146) of districts resported atleast one case since the beginning of the outbreak and 41%(60/146) reporting new cases in the past 21 days.
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Two additional Mpox-related deaths were reported. A 24-year-old male from Buhweju District who was newly diagnosed with HIV and initiated on ART; and a 26-year-old male from Mbarara City admitted to Mbarara RRH on 7th May with moderate Mpox, known HIV-positive on ART, whose condition deteriorated and passed on 27th May 2025.
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High-risk mortality observed. A total of 44 deaths have occurred among confirmed cases, over half (52.3%) of whom were co-infected with HIV, underscoring vulnerabilities in this population. Persons co-infected with HIV had four times higher odds of severe Mpox disease
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Young adults are disproportionately affected. Attack rates are highest among females aged 25–29 (2.7/100,000). In the last 3 weeks, there has been a shift in the most affected among males from 35-39 tomales aged 44–49 (4.1/100,000). This may be indicative of a shift in the transmission dynamics among males.