Cholera outbreaks have been confirmed in 9 (32%) of 28 states countrywide. The affected states include Imatong, Eastern Lakes, Jubek, Terekeka, Jonglei, Western Bieh, Northern Liech, Southern Liech; and Eastern Nile (Table 1 and Figure 1.0). Suspect cholera cases have been reported in Mayendit, Panyijiar, and Ayod (Table 4). Cumulatively 128 (34.7 %) of the samples tested positive for Vibrio Cholerae inaba in the National Public Health Laboratory as of 1 December 2016 (Table 3). Jubek state has recorded 2,006 cholera cases including 27 deaths (CFR 1.35 %). No new cholera case was reported in Jubek State during week 48 of 2016 (Table 1 and Figure 1.1).