The women had gone to a hill forest to cut fuel wood and were taking shelter from a heavy downpour when a landslide swept them away.
Rescue efforts were underway, but the officials said it was unlikely that the women would be found alive.
The Nepal Red Cross Society said the death toll from landslides and floods in different parts of Nepal from June 10 to September 3 was 266, not including the most recent reported tradgedy.
Another 39 persons were missing, according to the society. Red Cross statistics indicate that 341 were injured and 1,968 displaced in the current rain-related disasters.
It said 10,108 families were affected, 1,458 houses destroyed and another 2,990 houses partially damaged. dpa sb sd
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