World Relief is assessing the situation and will be responding with assistance to the victims.
Early reports indicate that damage is widespread in the capital Port-au-Prince - and casualties could be severe.
Two strong aftershocks sparked fear and panic, and a tsunami alert was issued.
There were reports of extensive damage to buildings in the capital, including a hospital that reportedly collapsed.
An eyewitness at the scene reported that the city was "just gray with dust."
Haiti, the poorest nation in the western hemisphere, has suffered from several major disasters in recent years, including deadly hurricanes and floods.
World Relief works alongside local churches in Port-au-Prince and the surrounding area to combat AIDS, provide basic healthcare for mothers and infants, protect orphans and at-risk children and improve financial security for vulnerable households.
You can help Haiti now. Please give generously. Visit our website to donate.