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Equatorial Guinea

Marburg virus disease - Equatorial Guinea (9 June 2023)

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Situation at a glance

On 8 June 2023, after two consecutive incubation periods (42 days) without a new confirmed case reported, the Ministry of Health of Equatorial Guinea declared the end of the Marburg virus disease (MVD) outbreak, as per the WHO recommendations. A total of 17 confirmed and 23 probable cases were reported from five districts in four provinces; 12 of the 17 confirmed cases died and all of the probable cases were reported deaths.

WHO and partners provided technical support to the government to contain this outbreak through its country office.

WHO encourages maintaining most response activities for three months after the outbreak ends. This is to make sure that if the disease re-emerges, health authorities are able to detect it immediately, prevent the disease from spreading again, and ultimately save lives.

Description of the situation

On 13 February 2023, the Ministry of Health and Social Welfare of Equatorial Guinea declared an outbreak of MVD after suspected viral hemorrhagic fever deaths were reported between 7 January and 7 February 2023, and a case tested positive on 12 February for Marburg virus by real-time polymerase chain reaction (RT-PCR) at the Institut Pasteur de Dakar in Senegal.

From the outbreak declaration until 7 June 2023, 17 confirmed and 23 probable cases were reported in the continental region of Equatorial Guinea. Twelve of the confirmed cases died and all of the probable cases were reported deaths (the case fatality ratio among confirmed cases is 75%, excluding one confirmed case with an unknown outcome).

The last confirmed case admitted to a Marburg treatment center in Bata district in Litoral province was discharged on 26 April, after two consecutive negative PCR tests for MVD. On 8 June 2023, after two consecutive incubation periods (42 days) without a new confirmed case reported, the Ministry of Health of Equatorial Guinea declared the end of the outbreak.

Confirmed or probable cases were reported in five districts (Bata, Ebebiyin, Evinayong, Nsok Nsomo and Nsork) in four of the country's eight provinces (Centro Sur, Kié-Ntem, Litoral and Wele-Nzas).

Five cases (31%) were identified among healthcare workers, of whom two died (CFR among HCWs: 40%).

Four patients recovered and were enrolled in a survivor care programme to receive psychosocial and other post-recovery support.