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Key strategic developments in epidemiology
• Geographic Spread: Since 01 January 2024 and as of 27 October 2024, a total of 18 member states across the WHO African region have reported mpox cases, of which, 14 have active transmission. Active transmission is defined as cases being reported in the past six weeks.
• In the last reporting week, 573 new confirmed cases with one death were reported, accounted for in the total of 2,240 suspected cases including two potential related deaths report for the same period.
• Uganda reported the death of a confirmed mpox case involving a patient with HIV as a comorbidity.
Additionally, another death was reported from the Central African Republic after it occurred during epidemiological week 41. One case of clade Ib was identified in Germany, from an individual with travel history to Rwanda.
• Mauritius reported its first mpox case on 26 October 2024 in a traveler coming from Nigeria.
Epidemiological summary
Since 1 January 2022, cases of mpox have been reported to WHO from 20 Member States across the WHO African Region. As of 27 October 2024, a total of 11,852 laboratory confirmed cases, including 57 deaths, have been reported to WHO.
In 2024, as of 27 October 2024, 18 countries have documented 9,474 confirmed cases, including 35 deaths.
The three countries with most of the cases in 2024 are Democratic Republic of Congo, (n = 7,534), Burundi, (n = 1,419), and Uganda, (n = 167). Fourteen (14) countries are assessed as active: DRC, Burundi, CAR, Congo,
Ghana, Nigeria, Côte d’Ivoire, Liberia, Uganda, Kenya, Rwanda, Zambia, Zimbabwe, and Mauritius.
A significant number of suspected cases, that are clinically compatible with mpox are not tested due to limited diagnostic capacity and never get confirmed. For this reason, suspected cases are also shown in this section.
Care should be taken when interpreting these cases, as they are collected according to different case definitions.
In some countries, suspected cases that are negative after laboratory test are not removed from case counts.