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DR Congo + 19 more

Multi-country outbreak of mpox, external situation report #45 - 11 January 2025

Attachments

Highlights

• The outbreak of clade Ib monkeypox virus (MPXV) continues predominantly in the Democratic Republic of the Congo, Burundi and Uganda, with new travel-related cases identified in previously unaffected countries.

• Recent travel-associated mpox cases highlight the risk of undetected transmission in countries, emphasizing the need for strengthened surveillance and timely reporting to improve global monitoring and prevent international spread.

• The Democratic Republic of the Congo remains the most affected country, experiencing circulation of both clade I MPXV subclades. Despite many of the provinces reporting stable trends in cases, the situation in the country remains concerning with continued high circulation of the virus.

• Burundi and Uganda continue reporting between 100-200 new mpox cases per week, with a plateauing trend, possibly impacted by a decline in surveillance and reporting during the December festive season.

• Since the last update (23 December 2024), Uganda has reported six deaths, bringing the total to 12 deaths among confirmed mpox cases in the country.

• A travel-related case of mpox due to clade Ib MPXV i in Germany (the second importation) led to secondary household transmission.

• Clade Ib MPXV has been detected in three additional countries, Belgium, China and France, directly or indirectly linked to travel to affected countries in Central Africa.

• Kosovo has reported its first case of mpox. Information on the MPXV clade is not yet available.